Coenzyme Q10 prevents oxidative stress and fibrosis in isoprenaline induced cardiac remodeling in aged rats

Table 1 Effect of Co-Q10 on body weight, and organ wet weight of ISO treated rats

Parameters	Group
Parameters	Control	ISO	ISO + CoQ10
Initial body weight (g)	234.80 ± 19.31 ns	252.02 ± 6.57 ns	252.56 ± 7.91 ns
Final body Weight (g)	266.53 ± 19.56 ns	249.55 ± 7.91 ns	266.21 ± 9.97 ns
Heart Wet Weight (g/100 g of body weight)	0.26 ± 0.01 ns	0.37 ± 0.01 ns	0.32 ± 0.01 ns
LV(g/100 g of body weight)	0.21 ± 0.01a	0.29 ± 0.01b	0.23 ± 0.01a
RV(g/100 g of body weight)	0.04 ± 0.00 ns	0.05 ± 0.01 ns	0.05 ± 0.01 ns
Kidney(g/100 g of body weight)	0.54 ± 0.02a	0.64 ± 0.02b	0.55 ± 0.02a
Spleen(g/100 g of body weight)	0.33 ± 0.02 ns	0.34 ± 0.01 ns	0.30 ± 0.01 ns

Data are presented as mean ± SEM, n = 6. Statistical analysis was done as One way ANOVA with Newman Keuls test as post hoc test, which was conducted using Prism software (USA). a vs b is significantly different at p < 0.05. a vs b, control vs ISO or ISO vs ISO + CoQ10. Others are not significant

ISSN: 2050-6511