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Table 4 Characteristics of study population with and without DRP

From: Drug-related problems and medication reviews among old people with dementia

  People with DRPs N = 140 People without DRP n = 72 Simple OR (95% CI) Multiple OR (95% CI)
Cases n (%) 140 (66.0) 72 (33.9)   
Women, n (%) 88 (62.9) 45 (62.5) 1.015 (0.564-1.827)  
Age mean ± SD 83.7 ± 6.6 82.0 ± 6.3 1.042 (0.997-1.088) 1.041 (0.994-1.090)
Number of drugs at randomization ± SD 9.3 ± 3.4 6.8 ± 3.4 1.255 (1.137-1.385) 1.241 (1.122-1.374)
Type of ward
 Orthopedic ward n (%) 20 (14.3) 9 (12.5) ref  
 Medical ward n (%) 120 (85.7) 63 (87.5) 0.857 (0.369-1.993)  
Type of living
 Living at home n (%) 91 (65.0) 55 (76.4) ref  
 Nursing home n (%) 49 (35.0) 17 (23.6) 1.742 (0.914-3.321)  
MMSE (0–30) ± SD 18.9 ± 4.8 20.7 ± 4.5 0.923 (0.842-1.013)  
Creatinine clearance (mL/min) 52.8 ± 22.3 55.0 ± 21.1 0.995 (0.983-1.008)  
Medical history
 Heart failure n (%) 50 (35.7) 22 (30.6) 1.263 (0.687-2.322)  
 Cardiac arrhythmia n (%) 40 (28.6) 22 (30.6) 0.909 (0.488-1.692)  
 Diabetes mellitus n (%) 43 (30.7) 18 (25.0) 1.330 (0.699-2.530)  
 Chronic obstructive pulmonary disease n (%) 10 (7.1) 6 (8.3) 0.846 (0.295-2.429)  
 Stroke, past n (%) 44 (31.4) 6 (12.0) 5.042 (2.032-12.509) 4.306 (1.685-11.005)
  1. Abbreviations: CI confidence interval, DRP drug-related problem, MMSE Mini Mental State Examination (n = 157), OR odds ratio, SD standard deviation. Creatinine clearance was based on P-creatinine applying the Cockcroft-Gault equation. The multivariate model includes significant variables as independent variables; number of medications at randomization, stroke and age (borderline significant)
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