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Fig. 14 | BMC Pharmacology and Toxicology

Fig. 14

From: Coenzyme Q10 protected against arsenite and enhanced the capacity of 2,3-dimercaptosuccinic acid to ameliorate arsenite-induced toxicity in mice

Fig. 14

The figure shows the effect of arsenite on the brain and the neuroprotective role of CoQ10 and DMSA. Mice were administered with 15 mg/kg arsenite alone or alongside 200 mg/kg of CoQ10 or 50 mg/kg DMSA independently or in combination. After 45 days’ post treatment, brain samples from the five treatment groups; normal control (a), arsenite (b), arsenite+CoQ10 (c), arsenite+DMSA (d) and arsenite+CoQ10 + DMSA (e) were collected and processed for histological examination using H&E staining. BV-blood vessels, Arrows indicated areas of gliosis

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