Meggio F, Pinna LA: One-thousand-and-one substrates of protein kinase CK2?. FASEB J. 2003, 17 (3): 349-368. 10.1096/fj.02-0473rev.
Article
CAS
PubMed
Google Scholar
Ahmed K, Gerber DA, Cochet C: Joining the cell survival squad: an emerging role for protein kinase CK2. Trends Cell Biol. 2002, 12 (5): 226-230. 10.1016/S0962-8924(02)02279-1.
Article
CAS
PubMed
Google Scholar
Hanif IM, Pervaiz S: Repressing the activity of protein kinase CK2 releases the brakes on mitochondria-mediated apoptosis in cancer cells. Curr Drug Targets. 2011, 12 (6): 902-908. 10.2174/138945011795528831.
Article
CAS
PubMed
Google Scholar
Ghavidel A, Hockman DJ, Schultz MC: A review of progress towards elucidating the role of protein kinase CK2 in polymerase III transcription: regulation of the TATA binding protein. Mol Cell Biochem. 1999, 191 (1–2): 143-148.
Article
CAS
PubMed
Google Scholar
Ghavidel A, Schultz MC: TATA binding protein-associated CK2 transduces DNA damage signals to the RNA polymerase III transcriptional machinery. Cell. 2001, 106 (5): 575-584. 10.1016/S0092-8674(01)00473-1.
Article
CAS
PubMed
Google Scholar
Marin O, Sarno S, Boschetti M, Pagano MA, Meggio F, Ciminale V, D’Agostino DM, Pinna LA: Unique features of HIV-1 Rev protein phosphorylation by protein kinase CK2 (‘casein kinase-2’). FEBS Lett. 2000, 481 (1): 63-67. 10.1016/S0014-5793(00)01971-2.
Article
CAS
PubMed
Google Scholar
Meggio F, D’Agostino DM, Ciminale V, Chieco-Bianchi L, Pinna LA: Phosphorylation of HIV-1 Rev protein: implication of protein kinase CK2 and pro-directed kinases. Biochem Biophys Res Commun. 1996, 226 (2): 547-554. 10.1006/bbrc.1996.1392.
Article
CAS
PubMed
Google Scholar
Enomoto M, Sawano Y, Kosuge S, Yamano Y, Kuroki K, Ohtsuki K: High phosphorylation of HBV core protein by two alpha-type CK2-activated cAMP-dependent protein kinases in vitro. FEBS Lett. 2006, 580 (3): 894-899. 10.1016/j.febslet.2006.01.011.
Article
CAS
PubMed
Google Scholar
Dal Pero F, Di Maira G, Marin O, Bortoletto G, Pinna LA, Alberti A, Ruzzene M, Gerotto M: Heterogeneity of CK2 phosphorylation sites in the NS5A protein of different hepatitis C virus genotypes. J Hepatol. 2007, 47 (6): 768-776. 10.1016/j.jhep.2007.07.020.
Article
CAS
PubMed
Google Scholar
Alvisi G, Jans DA, Guo J, Pinna LA, Ripalti A: A protein kinase CK2 site flanking the nuclear targeting signal enhances nuclear transport of human cytomegalovirus pp UL44. Traffic. 2005, 6 (11): 1002-1013. 10.1111/j.1600-0854.2005.00331.x.
Article
CAS
PubMed
Google Scholar
Guerra B, Issinger OG: Protein kinase CK2 in human diseases. Curr Med Chem. 2008, 15 (19): 1870-1886. 10.2174/092986708785132933.
Article
CAS
PubMed
Google Scholar
Lin KY, Tai C, Hsu JC, Li CF, Fang CL, Lai HC, Hseu YC, Lin YF, Uen YH: Overexpression of nuclear protein kinase CK2 alpha catalytic subunit (CK2alpha) as a poor prognosticator in human colorectal cancer. PLoS One. 2011, 6 (2): e17193-10.1371/journal.pone.0017193.
Article
CAS
PubMed
PubMed Central
Google Scholar
Zou J, Luo H, Zeng Q, Dong Z, Wu D, Liu L: Protein kinase CK2alpha is overexpressed in colorectal cancer and modulates cell proliferation and invasion via regulating EMT-related genes. J Transl Med. 2011, 9: 97-10.1186/1479-5876-9-97.
Article
CAS
PubMed
PubMed Central
Google Scholar
Homma MK, Li D, Krebs EG, Yuasa Y, Homma Y: Association and regulation of casein kinase 2 activity by adenomatous polyposis coli protein. Proc Natl Acad Sci U S A. 2002, 99 (9): 5959-5964. 10.1073/pnas.092143199.
Article
CAS
PubMed
PubMed Central
Google Scholar
Stalter G, Siemer S, Becht E, Ziegler M, Remberger K, Issinger OG: Asymmetric expression of protein kinase CK2 subunits in human kidney tumors. Biochem Biophys Res Commun. 1994, 202 (1): 141-147. 10.1006/bbrc.1994.1904.
Article
CAS
PubMed
Google Scholar
Laramas M, Pasquier D, Filhol O, Ringeisen F, Descotes JL, Cochet C: Nuclear localization of protein kinase CK2 catalytic subunit (CK2alpha) is associated with poor prognostic factors in human prostate cancer. Eur J Cancer. 2007, 43 (5): 928-934. 10.1016/j.ejca.2006.11.021.
Article
CAS
PubMed
Google Scholar
Yenice S, Davis AT, Goueli SA, Akdas A, Limas C, Ahmed K: Nuclear casein kinase 2 (CK-2) activity in human normal, benign hyperplastic, and cancerous prostate. Prostate. 1994, 24 (1): 11-16. 10.1002/pros.2990240105.
Article
CAS
PubMed
Google Scholar
Giusiano S, Cochet C, Filhol O, Duchemin-Pelletier E, Secq V, Bonnier P, Carcopino X, Boubli L, Birnbaum D, Garcia S: Protein kinase CK2alpha subunit over-expression correlates with metastatic risk in breast carcinomas: quantitative immunohistochemistry in tissue microarrays. Eur J Cancer. 2011, 47 (5): 792-801. 10.1016/j.ejca.2010.11.028.
Article
CAS
PubMed
Google Scholar
Eddy SF, Guo S, Demicco EG, Romieu-Mourez R, Landesman-Bollag E, Seldin DC, Sonenshein GE: Inducible IkappaB kinase/IkappaB kinase epsilon expression is induced by CK2 and promotes aberrant nuclear factor-kappaB activation in breast cancer cells. Cancer Res. 2005, 65 (24): 11375-11383. 10.1158/0008-5472.CAN-05-1602.
Article
CAS
PubMed
Google Scholar
Munstermann U, Fritz G, Seitz G, Lu YP, Schneider HR, Issinger OG: Casein kinase II is elevated in solid human tumours and rapidly proliferating non-neoplastic tissue. Eur J Biochem. 1990, 189 (2): 251-257. 10.1111/j.1432-1033.1990.tb15484.x.
Article
CAS
PubMed
Google Scholar
Landesman-Bollag E, Romieu-Mourez R, Song DH, Sonenshein GE, Cardiff RD, Seldin DC: Protein kinase CK2 in mammary gland tumorigenesis. Oncogene. 2001, 20 (25): 3247-3257. 10.1038/sj.onc.1204411.
Article
CAS
PubMed
Google Scholar
Sarno S, Pinna LA: Protein kinase CK2 as a druggable target. Mol Biosyst. 2008, 4 (9): 889-894. 10.1039/b805534c.
Article
CAS
PubMed
Google Scholar
Zhang J, Shan Y, Pan X, He L: Recent advances in antiangiogenic agents with VEGFR as target. Mini Rev Med Chem. 2011, 11 (11): 920-946. 10.2174/138955711797068355.
Article
CAS
PubMed
Google Scholar
Feher M, Schmidt JM: Property distributions: differences between drugs, natural products, and molecules from combinatorial chemistry. J Chem Inf Comput Sci. 2003, 43 (1): 218-227. 10.1021/ci0200467.
Article
CAS
PubMed
Google Scholar
Leach AR, Hann MM: The in silico world of virtual libraries. Drug Discov Today. 2000, 5 (8): 326-336. 10.1016/S1359-6446(00)01516-6.
Article
CAS
PubMed
Google Scholar
Pagano MA, Meggio F, Ruzzene M, Andrzejewska M, Kazimierczuk Z, Pinna LA: 2-Dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole: a novel powerful and selective inhibitor of protein kinase CK2. Biochem Biophys Res Commun. 2004, 321 (4): 1040-1044. 10.1016/j.bbrc.2004.07.067.
Article
CAS
PubMed
Google Scholar
Guo C, Yu S, Davis AT, Wang H, Green JE, Ahmed K: A potential role of nuclear matrix-associated protein kinase CK2 in protection against drug-induced apoptosis in cancer cells. J Biol Chem. 2001, 276 (8): 5992-5999. 10.1074/jbc.M004862200.
Article
CAS
PubMed
Google Scholar
Ahmad KA, Harris NH, Johnson AD, Lindvall HC, Wang G, Ahmed K: Protein kinase CK2 modulates apoptosis induced by resveratrol and epigallocatechin-3-gallate in prostate cancer cells. Mol Cancer Ther. 2007, 6 (3): 1006-1012. 10.1158/1535-7163.MCT-06-0491.
Article
CAS
PubMed
Google Scholar
Ruzzene M, Penzo D, Pinna LA: Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells. Biochem J. 2002, 364 (Pt 1): 41-47.
Article
CAS
PubMed
PubMed Central
Google Scholar
Yde CW, Frogne T, Lykkesfeldt AE, Fichtner I, Issinger OG, Stenvang J: Induction of cell death in antiestrogen resistant human breast cancer cells by the protein kinase CK2 inhibitor DMAT. Cancer Lett. 2007, 256 (2): 229-237. 10.1016/j.canlet.2007.06.010.
Article
CAS
PubMed
Google Scholar
Di Maira G, Salvi M, Arrigoni G, Marin O, Sarno S, Brustolon F, Pinna LA, Ruzzene M: Protein kinase CK2 phosphorylates and upregulates Akt/PKB. Cell Death Differ. 2005, 12 (6): 668-677. 10.1038/sj.cdd.4401604.
Article
CAS
PubMed
Google Scholar
Duncan JS, Litchfield DW: Too much of a good thing: the role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2. Biochim Biophys Acta. 2008, 1784 (1): 33-47. 10.1016/j.bbapap.2007.08.017.
Article
CAS
PubMed
Google Scholar
Ponce DP, Maturana JL, Cabello P, Yefi R, Niechi I, Silva E, Armisen R, Galindo M, Antonelli M, Tapia JC: Phosphorylation of AKT/PKB by CK2 is necessary for the AKT-dependent up-regulation of beta-catenin transcriptional activity. J Cell Physiol. 2011, 226 (7): 1953-1959. 10.1002/jcp.22527.
Article
CAS
PubMed
Google Scholar
Kirihata Y, Kawarabayashi T, Imanishi S, Sugimoto M, Kume S: Coumestrol decreases intestinal alkaline phosphatase activity in post-delivery mice but does not affect vitamin D receptor and calcium channels in post-delivery and neonatal mice. J Reprod Dev. 2008, 54 (1): 35-41. 10.1262/jrd.19095.
Article
CAS
PubMed
Google Scholar
Greendale GA, Huang MH, Leung K, Crawford SL, Gold EB, Wight R, Waetjen E, Karlamangla AS: Dietary phytoestrogen intakes and cognitive function during the menopausal transition: results from the Study of Women’s Health Across the Nation Phytoestrogen Study. Menopause. 2012, 19 (8): 894-903. 10.1097/gme.0b013e318242a654.
Article
PubMed
PubMed Central
Google Scholar
Watanabe S, Yamaguchi M, Sobue T, Takahashi T, Miura T, Arai Y, Mazur W, Wahala K, Adlercreutz H: Pharmacokinetics of soybean isoflavones in plasma, urine and feces of men after ingestion of 60 g baked soybean powder (kinako). J Nutr. 1998, 128 (10): 1710-1715.
CAS
PubMed
Google Scholar
Mallis LM, Sarkahian AB, Harris HA, Zhang MY, McConnell OJ: Determination of rat oral bioavailability of soy-derived phytoestrogens using an automated on-column extraction procedure and electrospray tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2003, 796 (1): 71-86. 10.1016/j.jchromb.2003.08.003.
Article
CAS
PubMed
Google Scholar
Sun AS, Yeh HC, Wang LH, Huang YP, Maeda H, Pivazyan A, Hsu C, Lewis ER, Bruckner HW, Fasy TM: Pilot study of a specific dietary supplement in tumor-bearing mice and in stage IIIB and IV non-small cell lung cancer patients. Nutr Cancer. 2001, 39 (1): 85-95. 10.1207/S15327914nc391_12.
Article
CAS
PubMed
Google Scholar
Kuiper GG, Lemmen JG, Carlsson B, Corton JC, Safe SH, van der Saag PT, van der Burg B, Gustafsson JA: Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta. Endocrinology. 1998, 139 (10): 4252-4263. 10.1210/en.139.10.4252.
CAS
PubMed
Google Scholar
Jordan VC, Morrow M: Tamoxifen, raloxifene, and the prevention of breast cancer. Endocr Rev. 1999, 20 (3): 253-278. 10.1210/er.20.3.253.
CAS
PubMed
Google Scholar
Brzozowski AM, Pike AC, Dauter Z, Hubbard RE, Bonn T, Engstrom O, Ohman L, Greene GL, Gustafsson JA, Carlquist M: Molecular basis of agonism and antagonism in the oestrogen receptor. Nature. 1997, 389 (6652): 753-758. 10.1038/39645.
Article
CAS
PubMed
Google Scholar
Pike AC, Brzozowski AM, Hubbard RE, Bonn T, Thorsell AG, Engstrom O, Ljunggren J, Gustafsson JA, Carlquist M: Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist. EMBO J. 1999, 18 (17): 4608-4618. 10.1093/emboj/18.17.4608.
Article
CAS
PubMed
PubMed Central
Google Scholar
Cummings SR, Eckert S, Krueger KA, Grady D, Powles TJ, Cauley JA, Norton L, Nickelsen T, Bjarnason NH, Morrow M: The effect of raloxifene on risk of breast cancer in postmenopausal women: results from the MORE randomized trial, multiple outcomes of raloxifene evaluation. JAMA. 1999, 281 (23): 2189-2197. 10.1001/jama.281.23.2189.
Article
CAS
PubMed
Google Scholar
Zheng W, Dai Q, Custer LJ, Shu XO, Wen WQ, Jin F, Franke AA: Urinary excretion of isoflavonoids and the risk of breast cancer. Cancer Epidemiol Biomarkers Prev. 1999, 8 (1): 35-40.
CAS
PubMed
Google Scholar
Masliah E, Iimoto DS, Mallory M, Albright T, Hansen L, Saitoh T: Casein kinase II alteration precedes tau accumulation in tangle formation. Am J Pathol. 1992, 140 (2): 263-268.
CAS
PubMed
PubMed Central
Google Scholar
Tapia JC, Torres VA, Rodriguez DA, Leyton L, Quest AF: Casein kinase 2 (CK2) increases survivin expression via enhanced beta-catenin-T cell factor/lymphoid enhancer binding factor-dependent transcription. Proc Natl Acad Sci U S A. 2006, 103 (41): 15079-15084. 10.1073/pnas.0606845103.
Article
CAS
PubMed
PubMed Central
Google Scholar
Siddiqui-Jain A, Drygin D, Streiner N, Chua P, Pierre F, O’Brien SE, Bliesath J, Omori M, Huser N, Ho C: CX-4945, an orally bioavailable selective inhibitor of protein kinase CK2, inhibits prosurvival and angiogenic signaling and exhibits antitumor efficacy. Cancer Res. 2010, 70 (24): 10288-10298. 10.1158/0008-5472.CAN-10-1893.
Article
CAS
PubMed
Google Scholar