Kris MG, Hesketh PJ, Somerfield MR, Feyer P, Clark-Snow R, Koeller JM, et al. American Society of Clinical Oncology guideline for antiemetics in oncology: update 2006. J Clin Oncol. 2006;24(18):2932–47.
Article
CAS
PubMed
Google Scholar
Rudd J, Andrews P. Mechanisms of acute, delayed, and anticipatory emesis induced by anticancer therapies. In: Hesketh PJ (ed) Management of nausea and vomiting in cancer and cancer treatment. Sudbury: Jones and Bartlett Publishers; 2005. pp. 15–66.
Tanihata S, Igarashi H, Suzuki M, Uchiyama T. Cisplatin-induced early and delayed emesis in the pigeon. Br J Pharmacol. 2000;130(1):132–8.
Article
CAS
PubMed
PubMed Central
Google Scholar
Yamakuni H, Sawai-Nakayama H, Imazumi K, Maeda Y, Matsuo M, Manda T, et al. Resiniferatoxin antagonizes cisplatin-induced emesis in dogs and ferrets. Eur J Pharmacol. 2002;442(3):273–8.
Article
CAS
PubMed
Google Scholar
Watson J, Gonsalves S, Fossa A, McLean S, Seeger T, Obach S, et al. The anti-emetic effects of CP-99,994 in the ferret and the dog: role of the NK1 receptor. Br J Pharmacol. 1995;115(1):84–94.
Article
CAS
PubMed
PubMed Central
Google Scholar
Andrews P, Davis C. The physiology of emesis induced by anti-cancer therapy. In: Reynolds J, Andrews PLR, Davis CJ (eds) Serotonin and the scientific basis of anti-emetic therapy. Oxford: Oxford Clinical Communications; 1995. pp. 25–49.
Okada F, Saito H, Matsuki N. Blockade of motion-and cisplatin-induced emesis by a 5-HT2 receptor agonist in Suncus murinus. Br J Pharmacol. 1995;114(5):931–4.
Article
CAS
PubMed
PubMed Central
Google Scholar
Darmani NA, Crim JL, Janoyan JJ, Abad J, Ramirez J. A re-evaluation of the neurotransmitter basis of chemotherapy-induced immediate and delayed vomiting: evidence from the least shrew. Brain Res. 2009;1248:40–58.
Article
CAS
PubMed
Google Scholar
Darmani NA, Wang Y, Abad J, Ray AP, Thrush GR, Ramirez J. Utilization of the least shrew as a rapid and selective screening model for the antiemetic potential and brain penetration of substance P and NK 1 receptor antagonists. Brain Res. 2008;1214:58–72.
Article
CAS
PubMed
PubMed Central
Google Scholar
Uchiyama T, Kaneko A, Ito R. A simple method for the detection of emetic action using pigeons. J Med Soc Toho. 1978;25:912–4.
Google Scholar
Tanihata S, Saitou Y, Saitou K, Uchiyama T. Experimental analysis of theophylline-induced emetic response in pigeons. Jpn Pharmacol Ther. 2001;29(1):19–24.
CAS
Google Scholar
Saitou Y, Arakawa S-I, Saitou K-I, Tanihata S. Mechanism of amantadine-induced vomiting in the pigeon. Oyo Yakuri. 2000;59(6):111–21.
Google Scholar
Muggia F. Platinum compounds 30 years after the introduction of cisplatin: implications for the treatment of ovarian cancer. Gynecol Oncol. 2009;112(1):275–81.
Article
CAS
PubMed
Google Scholar
Lorch JH, Goloubeva O, Haddad RI, Cullen K, Sarlis N, Tishler R, et al. Induction chemotherapy with cisplatin and fluorouracil alone or in combination with docetaxel in locally advanced squamous-cell cancer of the head and neck: long-term results of the TAX 324 randomised phase 3 trial. Lancet Oncol. 2011;12(2):153–9.
Article
CAS
PubMed
PubMed Central
Google Scholar
Köberle B, Tomicic MT, Usanova S, Kaina B. Cisplatin resistance: preclinical findings and clinical implications. Biochim Biophys Acta. 2010;1806(2):172–82.
PubMed
Google Scholar
Fernandez-Ortega P, Caloto M, Chirveches E, Marquilles R, San Francisco J, Quesada A, et al. Chemotherapy-induced nausea and vomiting in clinical practice: Impact on patients’ quality of life. Support Care Cancer. 2012;20(12):3141–8.
Article
CAS
PubMed
Google Scholar
Weijl N, Wipkink-Bakker A, Lentjes E, Berger H, Cleton F, Osanto S. Cisplatin combination chemotherapy induces a fall in plasma antioxidants of cancer patients. Ann Oncol. 1998;9(12):1331–7.
Article
CAS
PubMed
Google Scholar
Masuda H, Tanaka T, Takahama U. Cisplatin generates superoxide anion by interaction with DNA in a cell-free system. Biochem Biophys Res Commun. 1994;203(2):1175–80.
Article
CAS
PubMed
Google Scholar
Yoshida M, Fukuda A, Hara M, Terada A, Kitanaka Y, Owada S. Melatonin prevents the increase in hydroxyl radical-spin trap adduct formation caused by the addition of cisplatin in vitro. Life Sci. 2003;72(15):1773–80.
Article
CAS
PubMed
Google Scholar
Reuter S, Gupta SC, Chaturvedi MM, Aggarwal BB. Oxidative stress, inflammation, and cancer: how are they linked? Free Radic Biol Med. 2010;49(11):1603–16.
Article
CAS
PubMed
PubMed Central
Google Scholar
Pace A, Savarese A, Picardo M, Maresca V, Pacetti U, Del Monte G, et al. Neuroprotective effect of vitamin E supplementation in patients treated with cisplatin chemotherapy. J Clin Oncol. 2003;21(5):927–31.
Article
CAS
PubMed
Google Scholar
Sahin K, Tuzcu M, Gencoglu H, Dogukan A, Timurkan M, Sahin N, et al. Epigallocatechin-3-gallate activates Nrf2/HO-1 signaling pathway in cisplatin-induced nephrotoxicity in rats. Life Sci. 2010;87(7):240–5.
Article
CAS
PubMed
Google Scholar
Kart A, Cigremis Y, Karaman M, Ozen H. Caffeic acid phenethyl ester (CAPE) ameliorates cisplatin-induced hepatotoxicity in rabbit. Exp Toxicol Pathol. 2010;62(1):45–52.
Article
CAS
PubMed
Google Scholar
Celebi S, Gurdal MM, Ozkul MH, Yasar H, Balikci HH. The effect of intratympanic vitamin C administration on cisplatin-induced ototoxicity. Eur Arch Otorhinolaryngol. 2013;270(4):1293–7.
Article
PubMed
Google Scholar
Gupta Y, Sharma S. Antiemetic activity of antioxidants against cisplatin-induced emesis in dogs. Environ Toxicol Pharmacol. 1996;1(3):179–84.
Article
CAS
PubMed
Google Scholar
Torii Y, Mutoh M, Saito H, Matsuki N. Involvement of free radicals in cisplatin-induced emesis in Suncus murinus. Eur J Pharmacol. 1993;248(2):131–5.
CAS
PubMed
Google Scholar
da Silva Porto PAL, Laranjinha JAN, de Freitas VAP. Antioxidant protection of low density lipoprotein by procyanidins: structure/activity relationships. Biochem Pharmacol. 2003;66(6):947–54.
Article
PubMed
Google Scholar
Bagchi D, Bagchi M, Stohs SJ, Ray SD, Sen CK, Preuss HG. Cellular protection with proanthocyanidins derived from grape seeds. Ann N Y Acad Sci. 2002;957(1):260–70.
Article
CAS
PubMed
Google Scholar
Devi A, Jolitha AB, Ishii N. Grape seed proanthocyanidin extract (GSPE) and antioxidant defense in the brain of adult rats. Med Sci Monit. 2006;12(4):BR124–BR9.
CAS
PubMed
Google Scholar
Wang C-Z, Fishbein A, Aung HH, Mehendale SR, Chang W-T, Xie J-T, et al. Polyphenol contents in grape-seed extracts correlate with antipica effects in cisplatin-treated rats. J Altern Complement Med. 2005;11(6):1059–65.
Article
PubMed
Google Scholar
Yousef MI, Saad AA, El-Shennawy LK. Protective effect of grape seed proanthocyanidin extract against oxidative stress induced by cisplatin in rats. Food Chem Toxicol. 2009;47(6):1176–83.
Article
CAS
PubMed
Google Scholar
Kandemir F, Benzer E, Ozkaraca M, Ceribasi S, Yildirim NC, Ozdemir N. Protective antioxidant effects of grape seed extract in a cisplatin-induced hepatotoxicity model in rabbits. Rev Med Vet-Toulouse. 2012;163(11):539–45.
Google Scholar
Devi SA, Chandrasekar BS, Manjula K, Ishii N. Grape seed proanthocyanidin lowers brain oxidative stress in adult and middle-aged rats. Exp Gerontol. 2011;46(11):958–64.
Article
Google Scholar
Kunnel Shinomol G, Raghunath N, Mukunda Srinivas Bharath M. Prophylaxis with Bacopa monnieri attenuates acrylamide induced neurotoxicity and oxidative damage via elevated antioxidant function. Cent Nerv Syst Agents Med Chem. 2013;13(1):3–12.
Article
Google Scholar
Pase MP, Kean J, Sarris J, Neale C, Scholey AB, Stough C. The cognitive-enhancing effects of Bacopa monnieri: A systematic review of randomized, controlled human clinical trials. J Altern Complement Med. 2012;18(7):647–52.
Article
PubMed
Google Scholar
Sharma S, Gupta Y. Effect of antioxidants on cisplatin induced delay in gastric emptying in rats. Environ Toxicol Pharmacol. 1997;3(1):41–6.
Article
CAS
PubMed
Google Scholar
Kahol AP, Singh T, Tandon S, Gupta MM, Khanuja SPS. Process for the preparation of a extract rich in bacosides from the herb Bacopa monniera. Google Patents. US patent 6833143 B1, 21 Dec 2004. http://www.google.co.in/patents/US6833143.
Russo A, Borrelli F. Bacopa monniera, a reputed nootropic plant: an overview. Phytomedicine. 2005;12(4):305–17.
Article
CAS
PubMed
Google Scholar
Ullah I, Subhan F, Rudd JA, Rauf K, Alam J, Shahid M, et al. Attenuation of cisplatin-induced emetogenesis by standardized Bacopa monnieri extracts in the pigeon: Behavioral and neurochemical correlations. Planta Med. 2014;80(17):1569–79.
Article
CAS
PubMed
Google Scholar
Preziosi P, D’Amato M, Del Carmine R, Martire M, Pozzoli G, Navarra P. The effects of 5-HT3 receptor antagonists on cisplatin-induced emesis in the pigeon. Eur J Pharmacol. 1992;221(2):343–50.
Article
CAS
PubMed
Google Scholar
Bagchi D, Garg A, Krohn R, Bagchi M, Bagchi D, Balmoori J, et al. Protective effects of grape seed proanthocyanidins and selected antioxidants against TPA-induced hepatic and brain lipid peroxidation and DNA fragmentation, and peritoneal macrophage activation in mice. Gen Pharmacol-Vasc S. 1998;30(5):771–6.
Article
CAS
Google Scholar
Ding Y, Dai X, Jiang Y, Zhang Z, Bao L, Li Y, et al. Grape seed proanthocyanidin extracts alleviate oxidative stress and ER stress in skeletal muscle of low-dose streptozotocin-and high-carbohydrate/high-fat diet-induced diabetic rats. Mol Nutr Food Res. 2013;57(2):365–9.
Article
CAS
PubMed
Google Scholar
Shahid M, Subhan F. Protective effect of Bacopa monniera methanol extract against carbon tetrachloride induced hepatotoxicity and nephrotoxicity. Pharmacologyonline. 2014;2(2):18–28.
Google Scholar
Shahid M, Subhan F, Ullah I, Ali G, Alam J, Shah R. Beneficial effects of Bacopa monnieri extract on opioid induced toxicity. Heliyon. 2016;2(2):e00068.
Article
PubMed
PubMed Central
Google Scholar
Fukui H, Yamamoto M, Sasaki S, Sato S. Involvement of 5-HT3 receptors and vagal afferents in copper sulfate-and cisplatin-induced emesis in monkeys. Eur J Pharmacol. 1993;249(1):13–8.
Article
CAS
PubMed
Google Scholar
Forsyth D, Yoshizawa T, Morooka N, Tuite J. Emetic and refusal activity of deoxynivalenol to swine. Appl Environ Microbiol. 1977;34(5):547–52.
CAS
PubMed
PubMed Central
Google Scholar
Kamato T, Ito H, Nagakura Y, Nishida A, Yuki H, Yamano M, et al. Mechanisms of cisplatin-and m-chlorophenylbiguinide-induced emesis in ferrets. Eur J Pharmacol. 1993;238(2):369–76.
Article
CAS
PubMed
Google Scholar
Sharma S, Kochupillai V, Gupta S, Seth S, Gupta Y. Antiemetic efficacy of ginger (Zingiber officinale) against cisplatin-induced emesis in dogs. J Ethnopharmacol. 1997;57(2):93–6.
Article
CAS
PubMed
Google Scholar
Smith WL, Callaham EM, Alphin RS. The emetic activity of centrally administered cisplatin in cats and its antagonism by zacopride. J Pharm Pharmacol. 1988;40(2):142–3.
Article
CAS
PubMed
Google Scholar
Kwiatkowska M, Parker LA, Burton P, Mechoulam R. A comparative analysis of the potential of cannabinoids and ondansetron to suppress cisplatin-induced emesis in the Suncus murinus (house musk shrew). Psychopharmacology (Berl). 2004;174(2):254–9.
Article
CAS
Google Scholar
Takeda N, Hasegawa S, Morita M, Matsunaga T. Pica in rats is analogous to emesis: an animal model in emesis research. Pharmacol Biochem Be. 1993;45(4):817–21.
Article
CAS
Google Scholar
Navarra P, Martire M, del Carmine R, Pozzoli G, Preziosi P. A dual effect of some 5-HT3 receptor antagonists on cisplatin-induced emesis in the pigeon. Toxicol Lett. 1992;64:745–9.
Article
PubMed
Google Scholar
Hanzlik P, Wood D. The mechanism of digitalis-emesis in pigeons. J Pharmacol Exp Ther. 1929;37(1):67–100.
CAS
Google Scholar
Gupta G, Dhawan B. Blockade of reserpine emesis in pigeons. Arch Int Pharmacodyn Ther. 1960;128:481–90.
CAS
PubMed
Google Scholar
Hudzik TJ. Sigma ligand-induced emesis in the pigeon. Pharmacol Biochem Be. 1992;41(1):215–7.
Article
CAS
Google Scholar
Wolff MC, Leander JD. Comparison of the antiemetic effects of a 5-HT 1A agonist, LY228729, and 5-HT 3 antagonists in the pigeon. Pharmacol Biochem Be. 1995;52(3):571–5.
Article
CAS
Google Scholar
Wolff MC, Leander JD. Effects of a 5-HT 1A receptor agonist on acute and delayed cyclophosphamide-induced vomiting. Eur J Pharmacol. 1997;340(2):217–20.
Article
CAS
PubMed
Google Scholar
Tanihata S, Oda S, Kakuta S, Uchiyama T. Antiemetic effect of a tachykinin NK1 receptor antagonist GR205171 on cisplatin-induced early and delayed emesis in the pigeon. Eur J Pharmacol. 2003;461(2–3):197–206.
Article
CAS
PubMed
Google Scholar
Tanihata S, Oda S, Nakai S, Uchiyama T. Antiemetic effect of dexamethasone on cisplatin-induced early and delayed emesis in the pigeon. Eur J Pharmacol. 2004;484(2):311–21.
Article
CAS
PubMed
Google Scholar
Gylys J, Doran K, Buyniski J. Antagonism of cisplatin induced emesis in the dog. Res Commun Chem Pathol Pharmacol. 1979;23(1):61–8.
CAS
PubMed
Google Scholar
Nakayama H, Yamakuni H, Higaki M, Ishikawa H, Imazumi K, Matsuo M, et al. Antiemetic activity of FK1052, a 5-HT3-and 5-HT4-receptor antagonist, in Suncus murinus and ferrets. J Pharmacol Sci. 2005;98(4):396–403.
Article
CAS
PubMed
Google Scholar
Sangeetha P, Das U, Koratkar R, Suryaprabha P. Increase in free radical generation and lipid peroxidation following chemotherapy in patients with cancer. Free Radic Biol Med. 1990;8(1):15–9.
Article
CAS
PubMed
Google Scholar
Weijl N, Cleton F, Osanto S. Free radicals and antioxidants in chemotherapy induced toxicity. Cancer Treat Rev. 1997;23(4):209–40.
Article
CAS
PubMed
Google Scholar
Aapro M, Jordan K, Feyer P. Pathophysiology and classification of chemotherapy-induced nausea and vomiting. Prevention of nausea and vomiting in cancer patients. London: Springer Healthcare; 2013. p. 5–14.
Andrews PL, Horn CC. Signals for nausea and emesis: Implications for models of upper gastrointestinal diseases. Auton Neurosci. 2006;125(1):100–15.
Article
PubMed
PubMed Central
Google Scholar
Block KI, Koch AC, Mead MN, Tothy PK, Newman RA, Gyllenhaal C. Impact of antioxidant supplementation on chemotherapeutic efficacy: a systematic review of the evidence from randomized controlled trials. Cancer Treat Rev. 2007;33(5):407–18.
Article
CAS
PubMed
Google Scholar
Ray S, Bagchi D, Lim PM, Bagchi M, Gross SM, Kothari SC, et al. Acute and long-term safety evaluation of a novel IH636 grape seed proanthocyanidin extract. Res Commun Mol Pathol Pharmacol. 2000;109(3–4):165–97.
Google Scholar
Abbas M, Subhan F, Mohani N, Rauf K, Ali G, Khan M. The involvement of opioidergic mechanisms in the activity of Bacopa monnieri extract and its toxicological studies. Afr J Pharm Pharmacol. 2011;5(8):1120–4.
Google Scholar
Chiba T. Effect of sulfur-containing compounds on experimental diabetes. VI.: Screening of hypoglycemic action of sulfur-containing compounds. Yakugaku Zasshi. 1969;89(8):1138–43.
CAS
PubMed
Google Scholar
Ash M, Ash I. Handbook of Preservatives. NY: Synapse Info Resources; 2004.
Google Scholar
Bagchi M, Milnes M, Williams C, Balmoori J, Ye X, Stohs S, et al. Acute and chronic stress-induced oxidative gastrointestinal injury in rats, and the protective ability of a novel grape seed proanthocyanidin extract. Nutr Res. 1999;19(8):1189–99.
Article
CAS
Google Scholar
Aung HH, Dey L, Mehendale S, Xie J-T, Wu JA, Yuan C-S. Scutellaria baicalensis extract decreases cisplatin-induced pica in rats. Cancer Chemother Pharmacol. 2003;52(6):453–8.
Article
CAS
PubMed
Google Scholar
Mehendale S, Aung H, Wang A, Yin J-J, Wang C-Z, Xie J-T, et al. American ginseng berry extract and ginsenoside Re attenuate cisplatin-induced kaolin intake in rats. Cancer Chemother Pharmacol. 2005;56(1):63–9.
Article
CAS
PubMed
Google Scholar
Deepak M, Amit A. ‘Bacoside B’ - the need remains for establishing identity. Fitoterapia. 2013;87(2013):7–10.
Article
CAS
PubMed
Google Scholar
Bhattacharya S, Bhattacharya A, Kumar A, Ghosal S. Antioxidant activity of Bacopa monniera in rat frontal cortex, striatum and hippocampus. Phytother Res. 2000;14(3):174–9.
Article
CAS
PubMed
Google Scholar
Rauf K, Subhan F, Sewell RDE. A bacoside containing Bacopa monnieri extract reduces both morphine hyperactivity plus the elevated striatal dopamine and serotonin turnover. Phytother Res. 2011;26:758–63.
Article
PubMed
Google Scholar
Hesketh P, Van Belle S, Aapro M, Tattersall F, Naylor R, Hargreaves R, et al. Differential involvement of neurotransmitters through the time course of cisplatin-induced emesis as revealed by therapy with specific receptor antagonists. Eur J Cancer. 2003;39(8):1074–80.
Article
CAS
PubMed
Google Scholar
M-o D, Morita T, Yamashita N, Nishida K, Yamaguchi O, Higuchi Y, et al. The antioxidant N-2-mercaptopropionyl glycine attenuates left ventricular hypertrophy in in vivo murine pressure-overload model. J Am Coll Cardiol. 2002;39(5):907–12.
Article
Google Scholar
Tanonaka K, Iwai T, Motegi K, Takeo S. Effects of N-(2-mercaptopropionyl)-glycine on mitochondrial function in ischemic–reperfused heart. Cardiovasc Res. 2003;57(2):416–25.
Article
CAS
PubMed
Google Scholar
Sharma S, Gupta S, Kochupillai V, Seth S, Gupta Y. Cisplatin-induced pica behaviour in rats is prevented by antioxidants with antiemetic activity. Environ Toxicol Pharmacol. 1997;3(2):145–9.
Article
CAS
PubMed
Google Scholar
Grober U. Antioxidants and other micronutrients in complementary oncology. Breast Care. 2009;4(1):13.
Article
PubMed
PubMed Central
Google Scholar
Suhail N, Bilal N, Khan H, Hasan S, Sharma S, Khan F, et al. Effect of vitamins C and E on antioxidant status of breast‐cancer patients undergoing chemotherapy. J Clin Pharm Ther. 2012;37(1):22–6.
Article
CAS
PubMed
Google Scholar
Mishra K, Ojha H, Chaudhury NK. Estimation of antiradical properties of antioxidants using DPPH assay: A critical review and results. Food Chem. 2012;130(4):1036–43.
Article
CAS
Google Scholar
Loo A, Jain K, Darah I. Antioxidant and radical scavenging activities of the pyroligneous acid from a mangrove plant, Rhizophora apiculata. Food Chem. 2007;104(1):300–7.
Article
CAS
Google Scholar
Chun-yang L. Measuring the antiradical efficiency of proanthocyanidin from grape seed by the DPPH · assay. J Food Sci Biotech. 2006;2:102–6.
Google Scholar
Yang Y, Kinoshita K, Koyama K, Takahashi K, Tai T, Nunoura Y, et al. Novel experimental model using free radical-induced emesis for surveying anti-emetic compounds from natural sources. Planta Med. 1999;65(06):574–6.
Article
CAS
PubMed
Google Scholar
Johnston KD, Lu Z, Rudd JA. Looking beyond 5-HT3 receptors: A review of the wider role of serotonin in the pharmacology of nausea and vomiting. Eur J Pharmacol. 2014;722:13–25.
Article
CAS
PubMed
Google Scholar
Miner WD, Sanger GJ. Inhibition of cisplatin-induced vomiting by selective 5-Hydroxytryptamine M-receptor antagonism. Br J Pharmacol. 1986;88(3):497–9.
Article
CAS
PubMed
PubMed Central
Google Scholar
Conklin KA. Dietary antioxidants during cancer chemotherapy: Impact on chemotherapeutic effectiveness and development of side effects. Nutr Cancer. 2000;37(1):1–18.
Article
CAS
PubMed
Google Scholar