Skip to main content

Articles

Page 2 of 25

  1. Our study aimed to assess the risk signals of antibiotic-associated diarrhea (AAD) caused by various antibiotics using real-world data and provide references for safe clinical applications.

    Authors: Haining Huang, Lanfang Li, Mingli Wu, Zhen Liu, Yanyan Zhao, Jing Peng, Xiaolei Ren and Shuai Chen
    Citation: BMC Pharmacology and Toxicology 2023 24:73
  2. Nebulizers are commonly used to treat respiratory diseases, which are a major cause of morbidity and mortality. While inhalation therapy with antibodies has been evaluated in preclinical studies and clinical t...

    Authors: Soon Woo Hong, Kyung Hwa Chang, Chang Jae Woo, Ho Chul Kim, Bong Seop Kwak, Bong Joo Park and Ki Chang Nam
    Citation: BMC Pharmacology and Toxicology 2023 24:70
  3. The prediction of intestinal absorption of various drugs based on computer simulations has been a reality. However, in vivo pharmacokinetic simulations and virtual bioequivalence evaluation based on GastroPlus...

    Authors: Lu Wang, Jinliang Chen, Wenjun Chen, Zourong Ruan, Honggang Lou, Dandan Yang and Bo Jiang
    Citation: BMC Pharmacology and Toxicology 2023 24:69
  4. Imidacloprid is a neonicotinoid insecticide belonging to the chloronicotinyl nitroguanidine chemical family. Toxicity of IMD for mammals in scientific studies has shown high mutagenic, immunotoxic, teratogenic...

    Authors: Amina Sardar, Mehwish David, Sarwat Jahan, Tayyaba Afsar, Aneela Ahmad, Asad Ullah, Ali Almajwal, Huma Shafique and Suhail Razak
    Citation: BMC Pharmacology and Toxicology 2023 24:68
  5. Atherosclerosis is a form of cardiovascular disease that affects the endothelium of the blood vessel. Series of events are involved in the pathophysiology of this disease which includes the breaking down of th...

    Authors: Temitope Akinwumi Ajani, Kenechukwu Obikeze, Zandisiwe E. Magwebu, Samuel Egieyeh and Chesa G. Chauke
    Citation: BMC Pharmacology and Toxicology 2023 24:67
  6. The study was designed to investigate effects of single intravenous injection of esketamine on the incidence of postpartum depression (PPD) after labor analgesia and explore the potential mechanisms.

    Authors: Bin Ling, Yun Zhu, Zelin Yan, Hao Chen, Hua Xu, Qi Wang, Wanyou Yu and Wei Wang
    Citation: BMC Pharmacology and Toxicology 2023 24:66
  7. Dyslipidemia, characterized by elevated levels of triglycerides (TG), low-density lipoprotein (LDL), total cholesterol (TC), and reduced levels of high-density lipoprotein (HDL), is a major risk factor for car...

    Authors: Mohsen Yousefi, Sahand Tehrani Fateh, Mahlagha Nikbaf-Shandiz, Fatemeh Gholami, Samira Rastgoo, Reza Bagher, Alireza Khadem, Farideh Shiraseb and Omid Asbaghi
    Citation: BMC Pharmacology and Toxicology 2023 24:65
  8. Adverse drug reactions (ADRs) caused by opioid drugs show individual differences. Our objective was to explore the association between gene polymorphism and ADRs induced by opioid drugs.

    Authors: Jing Yang, Ying-zi Sun, Qun-fang Li, Zheng Fu, Yu-yao Guan, Chao Song and Lei Zheng
    Citation: BMC Pharmacology and Toxicology 2023 24:64
  9. Pertuzumab is widely used for the treatment of HER2 + breast cancer. But its safety in the real world should be continuously monitored. So, we evaluated the safety of pertuzumab by pharmacovigilance analyze ba...

    Authors: Shu-peng Zou, Hai-yun Yang, Meng-ling Ouyang, Qian Cheng, Xuan Shi and Ming-hui Sun
    Citation: BMC Pharmacology and Toxicology 2023 24:62
  10. The potentially adverse effects of cannabis (marijuana), a common leisure compound, on male reproductive performance are a reason for concern. δ-9-tetrahydrocannabinol (THC), the primary active component of ma...

    Authors: Shadi Mohammadpour-Asl, Shiva Roshan-Milani, Amin Abdollahzade Fard and Ali Golchin
    Citation: BMC Pharmacology and Toxicology 2023 24:61
  11. Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by the degeneration of nigrostriatal dopaminergic neurons and movement impairment. Based on theories, neuroinflammatory proces...

    Authors: Zahra Salari, Ghorbangol Ashabi, Ali Fartoosi, Ahmad Fartoosi, Marjan Shariatpanahi, Mehdi Aghsami, Hamed Montazeri and Afshin Kheradmand
    Citation: BMC Pharmacology and Toxicology 2023 24:60
  12. Aluminum phosphide toxicity is a serious problem in many countries. Unfortunately, there is no specific antidote. N-acetylcysteine has been used in some studies as adjuvant therapy depending on to its antioxid...

    Authors: Heba Othman Shaker, Omar El Sayed Rageh, Maged Alnajar, Nesreen Fares Alshamaly, Walaa Abdelfattah Abdelmaged and Mohamed Abd-ElGawad
    Citation: BMC Pharmacology and Toxicology 2023 24:59
  13. The illicit use and abuse of gamma-hydroxybutyric acid (GHB) occurs due to its sedative/hypnotic and euphoric effects. Currently, there are no clinically available therapies to treat GHB overdose, and care foc...

    Authors: Hao Wei, Jieyun Cao, Tyler Fallert, Su Yeo and Melanie A. Felmlee
    Citation: BMC Pharmacology and Toxicology 2023 24:58
  14. Authors: Jui-Ting Chang, Yao-Jen Liang, Chia-Yu Hsu, Chao-Yi Chen, Po-Jung Chen, Yi-Feng Yang, Yen-Lin Chen, Dee Pei, Jin-Biou Chang and Jyh-Gang Leu
    Citation: BMC Pharmacology and Toxicology 2023 24:57

    The original article was published in BMC Pharmacology and Toxicology 2017 18:67

  15. Complications and fata toxicity induced by chemotherapy are the main challenge for clinical management of osteosarcoma. The identification of agents that can augment the efficacy of chemotherapy at lower doses...

    Authors: Zhaoming Han, Juguang Yang, Ping Wang, Feng Bian and Jiguang Jia
    Citation: BMC Pharmacology and Toxicology 2023 24:56
  16. Authors: Kaveh Gharanizadeh, Ali Mohammad Sharifi, Hamed Tayyebi, Razieh Heidari, Shayan Amiri and Sajad Noorigaravand
    Citation: BMC Pharmacology and Toxicology 2023 24:55

    The original article was published in BMC Pharmacology and Toxicology 2023 24:44

  17. AT-533 is a novel heat shock protein 90 inhibitor that exerting anti-inflammatory, antiviral, and antitumor efficacy. Furthermore, the gel made of AT-533 as raw material named AT-533 gel has the function of re...

    Authors: Lishan Zhong, Yanting Wu, Chen Huang, Kaisheng Liu, Cui-fang Ye, Zhe Ren and Yifei Wang
    Citation: BMC Pharmacology and Toxicology 2023 24:54
  18. Authors: Omnia I. Ismail, Eman S. Shaltout, Nora Z. Abdellah, Diab F. Hetta, Wael M. A. Abd El-Ghani, Lobna A. Abdelzaher, Ahmed Mohamed Mohamed Mahmoud, Asmaa M. Hasan, Noha A. Rashed and Noha Esmael Ebrahem
    Citation: BMC Pharmacology and Toxicology 2023 24:53
  19. Botulinum toxin (BoNT) injection is an important adjunctive method to treat sialorrhea. The purpose of this systematic review was to analyze the effect and safety of BoNT injections in the intervention of sial...

    Authors: Chun-Lan Yang, Jia-Peng Huang, Ying-chao Tan, Ting-ting Wang, Han Zhang and Yun Qu
    Citation: BMC Pharmacology and Toxicology 2023 24:52
  20. Chemotherapy resistance hinders the successful treatment of osteosarcoma (OS) to some extent. Previous studies have confirmed that metformin (Met) enhances apoptosis induced by chemotherapeutic drugs, but the ...

    Authors: Bowen Wu, Peng Li, Eryue Qiu and Jian Chen
    Citation: BMC Pharmacology and Toxicology 2023 24:50
  21. Authors: Julián Olalla, Javier Pérez-Stachowski, Begoña Tortajada, Alfonso Del Arco, Efrén Márquez, Javier De la Torre, Miriam Nieto, José María García de Lomas, José Luis Prada and Javier García-Alegría
    Citation: BMC Pharmacology and Toxicology 2023 24:49

    The original article was published in BMC Pharmacology and Toxicology 2018 19:63

  22. Polycystic ovarian syndrome (PCOS) is a multifactorial condition with metabolic-related complications, such as diabetic nephropathy and chronic renal disorder, which are the leading cause of renal transplant g...

    Authors: Al-Amin M. Bashir and Kehinde S. Olaniyi
    Citation: BMC Pharmacology and Toxicology 2023 24:48
  23. Lopinavir/ritonavir (LPV/r) is a drug traditionally used for the treatment of HIV that has been repurposed as a potential post-exposure prophylaxis agent against COVID-19 in the COronavirus Post-Exposure Proph...

    Authors: Paul Thoueille, Margot Delfraysse, Pascal Andre, Thierry Buclin, Laurent A. Decosterd, Chiara Fedeli, Pilar Ustero, Alexandra Calmy and Monia Guidi
    Citation: BMC Pharmacology and Toxicology 2023 24:47
  24. Our previous clinical trial showed that etomidate requirements to reach an appropriate level of anesthesia in patients with obstructive jaundice were reduced, which means that these patients are more sensitive...

    Authors: Hao Gao, Qian Zhao, Jian-Gang Song, Guo-Xia Hu, Wei-Feng Yu, Ying-Fu Jiao and Jin-Chao Song
    Citation: BMC Pharmacology and Toxicology 2023 24:46
  25. The study aims to investigate the apoptotic effects of combining LBH589 and AM1241 (a selective CB2 receptor agonist) on cervical cancer cells and elucidating the mechanism of this combined therapy, which may ...

    Authors: Bo Sheng, Wenwen Wang, Dongyue Xia and Xiangdong Qu
    Citation: BMC Pharmacology and Toxicology 2023 24:45
  26. Deferoxamine (DFO) angiogenesis induction potential has been demonstrated in earlier studies, but not in the osteonecrosis of the femoral head (ONFH). In this study, we evaluated the outcome of ONFH treated wi...

    Authors: Kaveh Gharanizadeh, Ali Mohammad Sharifi, Hamed Tayyebi, Razieh Heidari, Shayan Amiri and Sajad Noorigaravand
    Citation: BMC Pharmacology and Toxicology 2023 24:44

    The Correction to this article has been published in BMC Pharmacology and Toxicology 2023 24:55

  27. Hepatocellular carcinoma (HCC) can be produced from aflatoxin B1 (AFB1) administration. Although berberine (BER) acts as an anticancer agent and can counteract the AFB1 effect, it has low bioavailability. Nano...

    Authors: Sarah M. Khedr, Doaa A. Ghareeb, Shadia A. Fathy and Germine M. Hamdy
    Citation: BMC Pharmacology and Toxicology 2023 24:42
  28. drug overdose is a common type of medication error, which caused significant patient injuries and economic losses. To determine which drugs are reported most frequently in association with drug overdose, a com...

    Authors: Jiaqi Ni, Xinru Tang and Li Chen
    Citation: BMC Pharmacology and Toxicology 2023 24:41
  29. This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s40360-019-0335-5.

    Authors: Ruqayya Afridi, Ashraf Ullah Khan, Sidra Khalid, Bushra Shal, Hina Rasheed, Muhammad Zia Ullah, Omer Shehzad, Yeong Shik Kim and Salman Khan
    Citation: BMC Pharmacology and Toxicology 2023 24:39
  30. The rapid worldwide spread of COVID-19 has caused a global health challenge with high mortality of severe or critically ill patients with COVID-19. To date, there is no specific efficient therapeutics for seve...

    Authors: Dawei Yang, Minjie Ju, Hao Wang, Yichen Jia, Xiaodan Wang, Hao Fang and Jia Fan
    Citation: BMC Pharmacology and Toxicology 2023 24:38
  31. There is a possibility for exposed lactating mammalians to transfer some contaminants to their milk. This study aimed to determine the levels and changes of Zearalenone (ZEN), Deoxynivalenol (DON) mycotoxins f...

    Authors: Bülent Güneş, Suzan Yalçın and Sıddika Songül Yalçın
    Citation: BMC Pharmacology and Toxicology 2023 24:37
  32. The biosimilar landscape for malignancies continues to grow, with several biosimilars for reference product bevacizumab currently available. Bevacizumab has been shown to be well tolerated; however, the safety...

    Authors: Hongtao Li, Xiangdi Zhao, Jing Xie, Xingyu Zhu, Yue Su, Cuixia He, Jiaxiang Ding, Minhui Zhu, Yuanyuan Xu, Ying Wang, Rongfang Shan, Bingyan Liu, Yuzhou Ding, Yuanyuan Liu, Huan Zhou and Yunqiu Xie
    Citation: BMC Pharmacology and Toxicology 2023 24:36
  33. Good-quality drugs that fulfill the regulatory parameters and are produced per the current good manufacturing practice (cGMP) standards are very critical for the best therapeutic outcomes. However, the variety...

    Authors: Biset Asrade, Ejigu Tessema and Abebe Tarekegn
    Citation: BMC Pharmacology and Toxicology 2023 24:35
  34. Drug overdose (OD) deaths in the U.S. continue to rise. After opioids, benzodiazepines (BZD) are the medication most commonly involved in prescription overdoses, yet OD risk factors among those prescribed BZD ...

    Authors: Donovan T. Maust, Amy S. B. Bohnert, Julie Strominger and Jason E. Goldstick
    Citation: BMC Pharmacology and Toxicology 2023 24:34
  35. Methamphetamine is widely abused in all parts of the world. It has been reported that short-term and long-term methamphetamine exposure could damage the dopaminergic system and induce cardiomyopathy and cardio...

    Authors: Mohammad Shabani, Zhaleh Jamali, Deniz Bayrami and Ahmad Salimi
    Citation: BMC Pharmacology and Toxicology 2023 24:33
  36. Many trials supported pembrolizumab as a first-line monotherapy to significantly improve overall survival (OS) in selected patients with previously untreated metastatic Non–Small Cell Lung Cancer (mNSCLC) and ...

    Authors: Lisa Faoro, Adriana Brusegan, Alberto Russi, Vincenzo Calderone, Alma Martelli, Ettore Marranconi, Debora Carpanese, Elena Berti and Marina Coppola
    Citation: BMC Pharmacology and Toxicology 2023 24:32
  37. Nonalcoholic fatty liver disease (NAFLD) is the most prevalent chronic hepatic disorder. The naturally occurring phytosterol; β-sitosterol has antiobesogenic and anti-diabetic properties. The purpose of this s...

    Authors: Omayma AR Abo-Zaid, Fatma SM Moawed, Effet Soliman Ismail and Mostafa A. Farrag
    Citation: BMC Pharmacology and Toxicology 2023 24:31
  38. First-generation epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), such as erlotinib, have been shown to target tumors with L858R (exon 21) and exon 19 deletions, resulting in significan...

    Authors: Xiangdan Cuan, Xingying Yang, Weiwei Zhu, Yue Zhao, Rui Luo, Yanping Huang, Xuanjun Wang and Jun Sheng
    Citation: BMC Pharmacology and Toxicology 2023 24:29
  39. Stroke is one of the most common noncommunicable diseases, with significant public health implications both globally and in Malaysia. The aim of this study was to evaluate post-stroke survivability as well as ...

    Authors: Monica Danial, Nurul Shahira Izwani Mohdradzi, Amer Hayat Khan, Alan Swee Hock Ch’ng and Looi Irene
    Citation: BMC Pharmacology and Toxicology 2023 24:28
  40. Atopic dermatitis (AD) is a chronic inflammatory skin disease that affects from children to adults widely, presenting symptoms such as pruritus, erythema, scaling, and dryness. Lupeol, a pentacyclic triterpeno...

    Authors: Sojung Bae, Na-Hee Jeong, Young-Ae Choi, Byungheon Lee, Yong Hyun Jang, Soyoung Lee and Sang-Hyun Kim
    Citation: BMC Pharmacology and Toxicology 2023 24:27
  41. Medical therapies can cause cardiotoxicity. Chloroquine (QC) and hydroxychloroquine (HQC) are drugs used in the treatment of malaria and skin and rheumatic disorders. These drugs were considered to help treatm...

    Authors: Enayatollah Seydi, Mozhgan Karbalaei Hassani, Saghi Naderpour, Abdollah Arjmand and Jalal Pourahmad
    Citation: BMC Pharmacology and Toxicology 2023 24:26
  42. Previous studies on animal models have suggested that δ-opioid receptor (OR) signaling is the primary pathway responsible for opioids' cardioprotective effect. We hypothesize that the μ-OR's activation protect...

    Authors: Marcin Kunecki, Tomasz Oleksy, Jan Martynów, Michalina Zygmunt, Marek Deja, Tomasz Kargul, Jolanta Biernat, Piotr Podolec, Krzysztof S. Gołba and Wojciech Płazak
    Citation: BMC Pharmacology and Toxicology 2023 24:25
  43. Renin–angiotensin–aldosterone system (RAAS) is hypothesized to be in the center of COVID pathophysiology as the angiotensin converting enzyme 2 (ACE2) represents the main entrance of the virus, thus there is a...

    Authors: Sarah Farid fahmy, Marwa Omar El Derany, Hazem Khorshid, Ayman Saleh and Ebtehal El-Demerdash
    Citation: BMC Pharmacology and Toxicology 2023 24:24
Reviewer acknowledgments

Annual Journal Metrics

  • Citation Impact 2023
    Journal Impact Factor: 2.8
    5-year Journal Impact Factor: 2.8
    Source Normalized Impact per Paper (SNIP): 0.774
    SCImago Journal Rank (SJR): 0.710

    Speed 2023
    Submission to first editorial decision (median days): 25
    Submission to acceptance (median days): 178

    Usage 2023
    Downloads: 790,731
    Altmetric mentions: 400

Peer-review Terminology

  • The following summary describes the peer review process for this journal:

    Identity transparency: Single anonymized

    Reviewer interacts with: Editor

    Review information published: Review reports. Reviewer Identities reviewer opt in. Author/reviewer communication

    More information is available here

Sign up for article alerts and news from this journal