Skip to main content

Articles

Page 2 of 24

  1. Authors: Kaveh Gharanizadeh, Ali Mohammad Sharifi, Hamed Tayyebi, Razieh Heidari, Shayan Amiri and Sajad Noorigaravand
    Citation: BMC Pharmacology and Toxicology 2023 24:55

    The original article was published in BMC Pharmacology and Toxicology 2023 24:44

  2. AT-533 is a novel heat shock protein 90 inhibitor that exerting anti-inflammatory, antiviral, and antitumor efficacy. Furthermore, the gel made of AT-533 as raw material named AT-533 gel has the function of re...

    Authors: Lishan Zhong, Yanting Wu, Chen Huang, Kaisheng Liu, Cui-fang Ye, Zhe Ren and Yifei Wang
    Citation: BMC Pharmacology and Toxicology 2023 24:54
  3. Authors: Omnia I. Ismail, Eman S. Shaltout, Nora Z. Abdellah, Diab F. Hetta, Wael M. A. Abd El-Ghani, Lobna A. Abdelzaher, Ahmed Mohamed Mohamed Mahmoud, Asmaa M. Hasan, Noha A. Rashed and Noha Esmael Ebrahem
    Citation: BMC Pharmacology and Toxicology 2023 24:53
  4. Botulinum toxin (BoNT) injection is an important adjunctive method to treat sialorrhea. The purpose of this systematic review was to analyze the effect and safety of BoNT injections in the intervention of sial...

    Authors: Chun-Lan Yang, Jia-Peng Huang, Ying-chao Tan, Ting-ting Wang, Han Zhang and Yun Qu
    Citation: BMC Pharmacology and Toxicology 2023 24:52
  5. Chemotherapy resistance hinders the successful treatment of osteosarcoma (OS) to some extent. Previous studies have confirmed that metformin (Met) enhances apoptosis induced by chemotherapeutic drugs, but the ...

    Authors: Bowen Wu, Peng Li, Eryue Qiu and Jian Chen
    Citation: BMC Pharmacology and Toxicology 2023 24:50
  6. Authors: Julián Olalla, Javier Pérez-Stachowski, Begoña Tortajada, Alfonso Del Arco, Efrén Márquez, Javier De la Torre, Miriam Nieto, José María García de Lomas, José Luis Prada and Javier García-Alegría
    Citation: BMC Pharmacology and Toxicology 2023 24:49

    The original article was published in BMC Pharmacology and Toxicology 2018 19:63

  7. Polycystic ovarian syndrome (PCOS) is a multifactorial condition with metabolic-related complications, such as diabetic nephropathy and chronic renal disorder, which are the leading cause of renal transplant g...

    Authors: Al-Amin M. Bashir and Kehinde S. Olaniyi
    Citation: BMC Pharmacology and Toxicology 2023 24:48
  8. Lopinavir/ritonavir (LPV/r) is a drug traditionally used for the treatment of HIV that has been repurposed as a potential post-exposure prophylaxis agent against COVID-19 in the COronavirus Post-Exposure Proph...

    Authors: Paul Thoueille, Margot Delfraysse, Pascal Andre, Thierry Buclin, Laurent A. Decosterd, Chiara Fedeli, Pilar Ustero, Alexandra Calmy and Monia Guidi
    Citation: BMC Pharmacology and Toxicology 2023 24:47
  9. Our previous clinical trial showed that etomidate requirements to reach an appropriate level of anesthesia in patients with obstructive jaundice were reduced, which means that these patients are more sensitive...

    Authors: Hao Gao, Qian Zhao, Jian-Gang Song, Guo-Xia Hu, Wei-Feng Yu, Ying-Fu Jiao and Jin-Chao Song
    Citation: BMC Pharmacology and Toxicology 2023 24:46
  10. The study aims to investigate the apoptotic effects of combining LBH589 and AM1241 (a selective CB2 receptor agonist) on cervical cancer cells and elucidating the mechanism of this combined therapy, which may ...

    Authors: Bo Sheng, Wenwen Wang, Dongyue Xia and Xiangdong Qu
    Citation: BMC Pharmacology and Toxicology 2023 24:45
  11. Deferoxamine (DFO) angiogenesis induction potential has been demonstrated in earlier studies, but not in the osteonecrosis of the femoral head (ONFH). In this study, we evaluated the outcome of ONFH treated wi...

    Authors: Kaveh Gharanizadeh, Ali Mohammad Sharifi, Hamed Tayyebi, Razieh Heidari, Shayan Amiri and Sajad Noorigaravand
    Citation: BMC Pharmacology and Toxicology 2023 24:44

    The Correction to this article has been published in BMC Pharmacology and Toxicology 2023 24:55

  12. Hepatocellular carcinoma (HCC) can be produced from aflatoxin B1 (AFB1) administration. Although berberine (BER) acts as an anticancer agent and can counteract the AFB1 effect, it has low bioavailability. Nano...

    Authors: Sarah M. Khedr, Doaa A. Ghareeb, Shadia A. Fathy and Germine M. Hamdy
    Citation: BMC Pharmacology and Toxicology 2023 24:42
  13. drug overdose is a common type of medication error, which caused significant patient injuries and economic losses. To determine which drugs are reported most frequently in association with drug overdose, a com...

    Authors: Jiaqi Ni, Xinru Tang and Li Chen
    Citation: BMC Pharmacology and Toxicology 2023 24:41
  14. This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s40360-019-0335-5.

    Authors: Ruqayya Afridi, Ashraf Ullah Khan, Sidra Khalid, Bushra Shal, Hina Rasheed, Muhammad Zia Ullah, Omer Shehzad, Yeong Shik Kim and Salman Khan
    Citation: BMC Pharmacology and Toxicology 2023 24:39
  15. The rapid worldwide spread of COVID-19 has caused a global health challenge with high mortality of severe or critically ill patients with COVID-19. To date, there is no specific efficient therapeutics for seve...

    Authors: Dawei Yang, Minjie Ju, Hao Wang, Yichen Jia, Xiaodan Wang, Hao Fang and Jia Fan
    Citation: BMC Pharmacology and Toxicology 2023 24:38
  16. There is a possibility for exposed lactating mammalians to transfer some contaminants to their milk. This study aimed to determine the levels and changes of Zearalenone (ZEN), Deoxynivalenol (DON) mycotoxins f...

    Authors: Bülent Güneş, Suzan Yalçın and Sıddika Songül Yalçın
    Citation: BMC Pharmacology and Toxicology 2023 24:37
  17. The biosimilar landscape for malignancies continues to grow, with several biosimilars for reference product bevacizumab currently available. Bevacizumab has been shown to be well tolerated; however, the safety...

    Authors: Hongtao Li, Xiangdi Zhao, Jing Xie, Xingyu Zhu, Yue Su, Cuixia He, Jiaxiang Ding, Minhui Zhu, Yuanyuan Xu, Ying Wang, Rongfang Shan, Bingyan Liu, Yuzhou Ding, Yuanyuan Liu, Huan Zhou and Yunqiu Xie
    Citation: BMC Pharmacology and Toxicology 2023 24:36
  18. Good-quality drugs that fulfill the regulatory parameters and are produced per the current good manufacturing practice (cGMP) standards are very critical for the best therapeutic outcomes. However, the variety...

    Authors: Biset Asrade, Ejigu Tessema and Abebe Tarekegn
    Citation: BMC Pharmacology and Toxicology 2023 24:35
  19. Drug overdose (OD) deaths in the U.S. continue to rise. After opioids, benzodiazepines (BZD) are the medication most commonly involved in prescription overdoses, yet OD risk factors among those prescribed BZD ...

    Authors: Donovan T. Maust, Amy S. B. Bohnert, Julie Strominger and Jason E. Goldstick
    Citation: BMC Pharmacology and Toxicology 2023 24:34
  20. Methamphetamine is widely abused in all parts of the world. It has been reported that short-term and long-term methamphetamine exposure could damage the dopaminergic system and induce cardiomyopathy and cardio...

    Authors: Mohammad Shabani, Zhaleh Jamali, Deniz Bayrami and Ahmad Salimi
    Citation: BMC Pharmacology and Toxicology 2023 24:33
  21. Many trials supported pembrolizumab as a first-line monotherapy to significantly improve overall survival (OS) in selected patients with previously untreated metastatic Non–Small Cell Lung Cancer (mNSCLC) and ...

    Authors: Lisa Faoro, Adriana Brusegan, Alberto Russi, Vincenzo Calderone, Alma Martelli, Ettore Marranconi, Debora Carpanese, Elena Berti and Marina Coppola
    Citation: BMC Pharmacology and Toxicology 2023 24:32
  22. Nonalcoholic fatty liver disease (NAFLD) is the most prevalent chronic hepatic disorder. The naturally occurring phytosterol; β-sitosterol has antiobesogenic and anti-diabetic properties. The purpose of this s...

    Authors: Omayma AR Abo-Zaid, Fatma SM Moawed, Effet Soliman Ismail and Mostafa A. Farrag
    Citation: BMC Pharmacology and Toxicology 2023 24:31
  23. First-generation epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), such as erlotinib, have been shown to target tumors with L858R (exon 21) and exon 19 deletions, resulting in significan...

    Authors: Xiangdan Cuan, Xingying Yang, Weiwei Zhu, Yue Zhao, Rui Luo, Yanping Huang, Xuanjun Wang and Jun Sheng
    Citation: BMC Pharmacology and Toxicology 2023 24:29
  24. Stroke is one of the most common noncommunicable diseases, with significant public health implications both globally and in Malaysia. The aim of this study was to evaluate post-stroke survivability as well as ...

    Authors: Monica Danial, Nurul Shahira Izwani Mohdradzi, Amer Hayat Khan, Alan Swee Hock Ch’ng and Looi Irene
    Citation: BMC Pharmacology and Toxicology 2023 24:28
  25. Atopic dermatitis (AD) is a chronic inflammatory skin disease that affects from children to adults widely, presenting symptoms such as pruritus, erythema, scaling, and dryness. Lupeol, a pentacyclic triterpeno...

    Authors: Sojung Bae, Na-Hee Jeong, Young-Ae Choi, Byungheon Lee, Yong Hyun Jang, Soyoung Lee and Sang-Hyun Kim
    Citation: BMC Pharmacology and Toxicology 2023 24:27
  26. Medical therapies can cause cardiotoxicity. Chloroquine (QC) and hydroxychloroquine (HQC) are drugs used in the treatment of malaria and skin and rheumatic disorders. These drugs were considered to help treatm...

    Authors: Enayatollah Seydi, Mozhgan Karbalaei Hassani, Saghi Naderpour, Abdollah Arjmand and Jalal Pourahmad
    Citation: BMC Pharmacology and Toxicology 2023 24:26
  27. Previous studies on animal models have suggested that δ-opioid receptor (OR) signaling is the primary pathway responsible for opioids' cardioprotective effect. We hypothesize that the μ-OR's activation protect...

    Authors: Marcin Kunecki, Tomasz Oleksy, Jan Martynów, Michalina Zygmunt, Marek Deja, Tomasz Kargul, Jolanta Biernat, Piotr Podolec, Krzysztof S. Gołba and Wojciech Płazak
    Citation: BMC Pharmacology and Toxicology 2023 24:25
  28. Renin–angiotensin–aldosterone system (RAAS) is hypothesized to be in the center of COVID pathophysiology as the angiotensin converting enzyme 2 (ACE2) represents the main entrance of the virus, thus there is a...

    Authors: Sarah Farid fahmy, Marwa Omar El Derany, Hazem Khorshid, Ayman Saleh and Ebtehal El-Demerdash
    Citation: BMC Pharmacology and Toxicology 2023 24:24
  29. Standard doses of second-generation H1-antihistamines (sgAHs) as first-line treatment are not always effective in treating chronic spontaneous urticaria (CSU), and hence an increase in the dose of sgAHs is recomm...

    Authors: Xianjun Xiao, Peiwen Xue, Yunzhou Shi, Junpeng Yao, Wei Cao, Leixiao Zhang, Zihao Zou, Siyuan Zhou, Chuan Wang, Mingling Chen, Rongjiang Jin, Ying Li and Qianhua Zheng
    Citation: BMC Pharmacology and Toxicology 2023 24:23
  30. Since the warnings by the United States (US) and European regulatory authorities in 2004 and 2005 it had been discussed whether there is some link between selective serotonin reuptake inhibitors (SSRIs) and su...

    Authors: Diana Dubrall, Stefanie Fekete, Sarah Leitzen, Lena Marie Paschke, Marcel Romanos, Matthias Schmid, Manfred Gerlach and Bernhardt Sachs
    Citation: BMC Pharmacology and Toxicology 2023 24:22
  31. Oral insulin administration has recently become one of the most exciting research subjects. Different approaches have been carried out to get an effective oral insulin delivery system using nanotechnology. The...

    Authors: Mohamed M. Fathy, Asmaa A. Hassan, Anwar A. Elsayed and Heba M. Fahmy
    Citation: BMC Pharmacology and Toxicology 2023 24:21
  32. The anti-osteosarcoma effects of hydrocortisone and thiram, an inhibitor of type 2 11ß-hydroxysteroid dehydrogenase (11HSD2), have not been reported. The purpose of this study was to investigate the effects of...

    Authors: You Zhang, Nanjing Li, He Li, Maojia Chen, Wei Jiang and Wenhao Guo
    Citation: BMC Pharmacology and Toxicology 2023 24:20
  33. The severe unfavorable effects of doxorubicin on the heart restrict its clinical usage. Numerous investigations document that cyclic GMP-AMP synthase (cGAS) activator of interferon genes (STING) cascade influe...

    Authors: Zilong Xiao, Ziqing Yu, Chaofeng Chen, Ruizhen Chen and Yangang Su
    Citation: BMC Pharmacology and Toxicology 2023 24:19
  34. Anabolic steroids (AS) are commonly abused by body builders and athletes aiming to increase their strength and muscle mass but unfortunately, the long-term use of AS may lead to serious side effects. Nandrolon...

    Authors: Dalia Abd Elwahab Hassan, Sherien S. Ghaleb, Amr reda Zaki, Ahmed Abdelmenem, Shimaa Nabil and Mostafa Abdallah Abdel Alim
    Citation: BMC Pharmacology and Toxicology 2023 24:17
  35. Cisplatin is a widely used and effective chemotherapeutic agent for most solid malignant tumors. However, cisplatin-induced ototoxicity is a common adverse effect that limits the therapeutic efficacy of tumors...

    Authors: Haiyan Wang, Hanqing Lin, Weibiao Kang, Lingfei Huang, Sisi Gong, Tao Zhang, Xiaotong Huang, Feinan He, Yongyi Ye, Yiyang Tang, Haiying Jia and Haidi Yang
    Citation: BMC Pharmacology and Toxicology 2023 24:16
  36. Osteonecrosis of the jaw (ONJ) is a rare but serious adverse drug reaction (ADR) commonly associated with bisphosphonate and denosumab therapy. Prior research utilized an online, public FDA Adverse Event Repor...

    Authors: Hardeep S. Ahdi, Thomas Adam Wichelmann, Sasirekha Pandravada and Eli D. Ehrenpreis
    Citation: BMC Pharmacology and Toxicology 2023 24:15
  37. Voriconazole is a second-generation triazole that is used to prevent and treat invasive fungal infections. The purpose of this study was to evaluate the pharmacokinetic equivalency of a test formulation and re...

    Authors: Xin Li, Chenjing Wang, Ping Shi, Yanping Liu, Ye Tao, Pingping Lin, Ting Li, Haixun Hu, Feifei Sun, Shuqin Liu, Yao Fu and Yu Cao
    Citation: BMC Pharmacology and Toxicology 2023 24:14
  38. Albumin-bound paclitaxel (nab-paclitaxel), as a special targeted preparation of paclitaxel, has the advantages of good curative effect and less side effects in anti-tumor therapy. The existence of the plasma-p...

    Authors: Jingjing Zhang, Luya Li, Jintuo Yin, Xidong Zhang, Ying Zheng and Rui Feng
    Citation: BMC Pharmacology and Toxicology 2023 24:13
  39. Chlorine is a chemical threat agent that can be harmful to humans. Inhalation of high levels of chlorine can lead to acute lung injury (ALI). Currently, there is no satisfactory treatment, and effective antido...

    Authors: Meng-meng Liu, Jiang-zheng Liu, Chen-qian Zhao, Peng Guo, Zhao Wang, Hao Wu, Weihua Yu, Rui Liu, Chun-xu Hai and Xiao-di Zhang
    Citation: BMC Pharmacology and Toxicology 2023 24:12
  40. Neurotoxicity is a severe side effect of platinum compounds used for cancer chemotherapy such as Cisplatin. This neurotoxicity leads to severe cognitive and nervous dysfunction, therefore, limiting the dose of...

    Authors: Eman A. Khalil, Hamdy Swelim, Hala El-Tantawi and Ahmed Abdellatif
    Citation: BMC Pharmacology and Toxicology 2023 24:11
  41. The study was aimed at evaluating the bioequivalence and safety of oseltamivir phosphate for suspension, provided by Shenzhen Beimei Pharmaceutical Co. Ltd. and manufactured by Hetero Labs Limited, and the ref...

    Authors: Ying Wang, Bangzhong Tang, Jing Xie, Xiaoqin Wang, Peng Ren, Guangmei Wu, Cuixia He, Minhui Zhu, Yue Su, Jiaxiang Ding, Yuanyuan Xu, Ling Fan, Qin Ge, Yuzhou Ding, Juan Zhu, Bingyan Liu…
    Citation: BMC Pharmacology and Toxicology 2023 24:10
  42. Seizures are considered to be the most common symptom encountered in emergency- rushed tramadol-poisoned patients; accounting for 8% of the drug-induced seizure cases. Although, diazepam clears these seizures,...

    Authors: Shaimaa A. ElShebiney, Rania Elgohary, Sayed H. Kenawy, Gehan T. El-Bassyouni and Esmat M. A. Hamzawy
    Citation: BMC Pharmacology and Toxicology 2023 24:9
  43. WIN55, 212–2 mesylate is a synthetic cannabinoid (SC) agonist of CB1 and CB2 receptors with much higher affinity to CB1 receptor than tetrahydrocannabinol and many potential therapeutic effects. Few studies ha...

    Authors: Ghada A. Omran, Eman S. H. Abd Allah, Sherine Ahmed Mohammed and Doaa M. El Shehaby
    Citation: BMC Pharmacology and Toxicology 2023 24:8
  44. Ezetimibe is a new class of antihyperlipidemic agent indicated for the prevention of atherosclerosis disease and for the treatment of hypercholesterolemia. Information on the pharmacokinetic profiles of ezetim...

    Authors: Feifei Sun, Yanping Liu, Ting Li, Pingping Lin, Xin Jiang, Xin Li, Chenjing Wang, Xiaomeng Gao, Yaping Ma, Yao Fu and Yu Cao
    Citation: BMC Pharmacology and Toxicology 2023 24:7
  45. Poisoning is a major health problem especially in developing countries and leads to high morbidity and mortality.

    Authors: Omar El-Sayed Rageh, Hamdy Khaled Sabra, Abdulrahman Abdullah Alammar, Omar Naif Alanazi, Ayman Nagy and Ibrahim Ali Kabbash
    Citation: BMC Pharmacology and Toxicology 2023 24:6
Reviewer acknowledgments

Annual Journal Metrics

  • 2022 Citation Impact
    2.9 - 2-year Impact Factor
    2.9 - 5-year Impact Factor
    0.932 - SNIP (Source Normalized Impact per Paper)
    0.603 - SJR (SCImago Journal Rank)

    2022 Speed
    26 days submission to first editorial decision for all manuscripts (Median)
    198 days submission to accept (Median)

    2022 Usage
    642,939 downloads
    1,154 Altmetric mentions

Peer-review Terminology

  • The following summary describes the peer review process for this journal:

    Identity transparency: Single anonymized

    Reviewer interacts with: Editor

    Review information published: Review reports. Reviewer Identities reviewer opt in. Author/reviewer communication

    More information is available here

Sign up for article alerts and news from this journal