Articles

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Decreased cervical epithelial sensitivity to nonoxynol-9 (N-9) after four daily applications in a murine model of topical vaginal microbicide safety

The disappointing clinical failures of five topical vaginal microbicides have provided new insights into factors that impact microbicide safety and efficacy. Specifically, the greater risk for human immunodefi...

Authors: Karissa Lozenski, Robert Ownbey, Brian Wigdahl, Tina Kish-Catalone and Fred C Krebs

Citation: BMC Pharmacology and Toxicology 2012 13:9

Content type: Research article Published on: 1 October 2012
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Low rates of hepatotoxicity among Asian patients with paracetamol overdose: a review of 1024 cases

The metabolism of paracetamol in Asians is thought to differ from Westerners. Detailed clinical features of paracetamol -induced hepatotoxicity among Asians remains largely unreported.

Authors: Abd-Rahman Marzilawati, Yen-Yew Ngau and Sanjiv Mahadeva

Citation: BMC Pharmacology and Toxicology 2012 13:8

Content type: Research article Published on: 28 September 2012
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Activation of kappa opioid receptors reduces seizure activity in a dose-dependent way

Authors: Luca Zangrandi and Christoph Schwarzer

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A91

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Peptidomics screening for the discovery of uterotonic plant peptides

Authors: Johannes Koehbach, Alfred F Attah, Margaret O’Brien, Michael Freissmuth and Christian W Gruber

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A89

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Neuropeptide Y modulates fear and fear extinction in distinct nuclei of the amygdala

Authors: Ramon O Tasan, Dilip Verma, Mario Mietzsch, Regine Heilbronn, Herbert Herzog and Günther Sperk

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A87

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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A TRPC3 blocker, Pyr3, prevents stent-induced arterial remodeling

Authors: Sarah König, Sara Browne, Heinrich Mächler, Gerald Höfler, C Oliver Kappe, Toma N Glasnov, Marlen Braune, Eric Wittchow and Klaus Groschner

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A85

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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TRPC3 overexpression promotes angiotensin II-induced cardiac dysfunction

Authors: Bernhard Doleschal, Stefan Wolf, Marie-Sophie Huber, Gerald Wölkart, Gudrun Antoons and Klaus Groschner

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A83

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Restricted collision coupling of the adenosine A_2Areceptor is due to its agonist-induced confinement in the membrane

Authors: Patrick Thurner, Simon Keuerleber, Ingrid Gsandtner, Christoph Gruber, Michael Freissmuth and Jürgen Zezula

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A81

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Activity of semicarbazide-sensitive amine oxidase in guinea-pig tissues is not affected by metformin

Authors: Katja Lukan and Simona Rajtar Osredkar

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A79

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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The influence of alpha-melanocortin enantiomers on acetaminophen-induced hepatis in mice

Authors: Petra Turčić, Karlo Houra, Mirna Bradamante, Paško Konjevoda, Tomislav Kelava and Nikola Štambuk

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A77

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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The galanin system in depression and antidepressant treatment: focus on the locus coeruleus

Authors: Simone B Sartori, Anupam Sah, Baosheng Zhao, Inga Neumann, Rainer Landgraf and Nicolas Singewald

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A75

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Expression of organic cation transporter 3 (SLC22A3) and plasma membrane monoamine transporter (SLC29A4) in human umbilical vein endothelial cells and their relevance for histamine uptake

Authors: Polonca Ferk, Metoda Lipnik-Štangelj, Mojca Kržan and Katarina Černe

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A73

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Bacterial peptidoglycan primes the immune system leading to increased sickness in response to lipopolysaccharide

Authors: Aitak Farzi, Evelin Painsipp and Peter Holzer

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A71

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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New structural determinants of charged local anaesthetic block of voltage-gated sodium channels

Authors: Péter Lukács, René Cervenka, Vaibhavkumar S Gawali, Xaver Koenig, Ágnes K Mike, Lena Rubi, Karlheinz Hilber and Hannes Todt

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A70

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Biophysical characterization of Ca_V1.4 L-type calcium channel mutants causing congenital stationary night blindness type 2 in humans

Authors: Klaus W Schicker, Verena Burtscher, Dagmar Knoflach, Anamika Singh, Thomas Stockner and Alexandra Koschak

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A69

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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IL-6-mediated migration of human metastatic melanoma cells is reduced by simvastatin treatment

Authors: Christine Wasinger, Christoph Minichsdorfer and Martin Hohenegger

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A66

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Statins impact on epigenetics of tumor cells

Authors: Murtaza Kulaksiz and Martin Hohenegger

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A64

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Does pulmonary surfactant generally affect antimicrobial activity?

Authors: Richard Schwameis, Sabine Strommer, Markus Zeitlinger and Robert Sauermann

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A62

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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A conformational change of the domain IV S6 segment of the voltage-gated sodium channel during inactivation

Authors: Vaibhavkumar S Gawali, René Cervenka, Péter Lukács, Xaver Koenig, Lena Rubi, Ágnes K Mike, Karlheinz Hiber and Hannes Todt

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A60

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Peptide YY and neuropeptide Y in regulation of pain and spatial learning and memory

Authors: Piyush Jain, Ahmed Hassan, Herbert Herzog and Peter Holzer

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A58

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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The N-terminus acts as a lever to support amphetamine-induced substrate efflux by the serotonin transporter

Authors: Sonja Sucic, Carina Kern, Harald H Sitte and Michael Freissmuth

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A54

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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LRET-based distance measurements in the mammalian glutamate transporter EAAT3

Authors: Kusumika Saha, SanthoshKannan Venkatesan, Azmat Sohail, Thomas Stockner, Simon Bulling, Gerhard F Ecker, Harald H Sitte and Walter Sandtner

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A52

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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A mouse model to study the C-terminal regulation of Ca_V1.3 L-type calcium channels

Authors: Anja Scharinger, Florian Hechenblaikner, Gabriella Bock, Mathias Gebhart, Kai Schönig, Dusan Bartsch, Anupam Sah, Nicolas Singewald, Martina J Sinnegger-Brauns and Jörg Striessnig

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A50

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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The differential effect of resveratrol on the renal artery of normal and diabetic rats

Authors: Ljiljana C Gojković-Bukarica, Vladimir I Kanjuh, Radmila B Novaković, Dragana D Protić, Jelena M Cvejić and Milica T Atanacković

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A48

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Functional implications of K_V7 channel phosphorylation

Authors: Isabella Salzer, Wei-Quiang Chen, Helmut Kubista, Gert Lubec, Stefan Boehm and Jae-Won Yang

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A46

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Neurobiological correlates of successful deep brain stimulation in a mouse model of high trait affect

Authors: Claudia Schmuckermair, Stefano Gaburro, Anupam Sah, Rainer Landgraf, Simone B Sartori and Nicolas Singewald

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A44

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Histone deacetylase inhibitors, glutamatergic drugs and deep brain stimulation rescue resistance to fear extinction in a genetic mouse model

Authors: Nigel Whittle, Claudia Schmuckermair, Ozge Gunduz Cinar, Markus Hauschild, Francesco Ferraguti, Andrew Holmes and Nicolas Singewald

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A42

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Uremia-induced lysine modifications transform plasma albumin into a high-density lipoprotein receptor inhibitor

Authors: Veronika Binder, Michael Holzer, Dalia El-Gamal, Sabine Dirnberger and Gunther Marsche

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A40

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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The anti-addiction drug ibogaine inhibits cardiac ion channels: a study to assess the drug’s proarrhythmic potential

Authors: Xaver Koenig, Michael Kovar, Lena Rubi, Ágnes K Mike, Péter Lukács, Vaibhavkumar S Gawali, Hannes Todt, Walter Sandtner and Karlheinz Hilber

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A38

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Tolerance to nitroglycerin through proteasomal degradation of aldehyde dehydrogenase-2 in a genetic mouse model of ascorbate deficiency

Authors: Astrid Schrammel, Gerald Wölkart, Matteo Beretta, Heike Stessel, Kurt Schmidt, Nobuyo Maeda and Bernd Mayer

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A36

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Plasma levels of an atropine/scopolamine mixture following ingestion of low doses as food contaminant

Authors: Lucija Perharič, Gordana Koželj and Lovro Stanovnik

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A34

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Influence of the 14-alkoxy group and the substitution in position 5 in N-methyl-14-alkoxymorphinan-6-ones on in vitro and in vivopharmacological activities

Authors: Tanila Ben Haddou, Roberta Lattanzi, Lucia Negri, Helmut Schmidhammer and Mariana Spetea

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A33

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Low affinity histamine uptake into neonatal rat astrocytes does not involve OCT

Authors: Vesna Terbuc, Maša Novak, Katja Perdan-Pirkmajer, Sergej Pirkmajer and Mojca Kržan

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A32

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Pharmacological applications of natural peptide libraries

Authors: Johannes Koehbach, Markus Muttenthaler, Carsten Gründemann and Christian W Gruber

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A31

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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The role of potassium channels in the mechanism of vasodilatation of human umbilical vein induced by resveratrol

Authors: Dragana D Protić, Radmila B Novaković, Svetlana Spremović-Radjenović, Nebojša V Radunović, Helmut Heinle, Vladimir I Kanjuh and Ljiljana C Gojković-Bukarica

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A29

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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The role of nitric oxide and endothelin on optic nerve head blood flow autoregulation

Authors: Doreen Schmidl, Agnes Boltz, Semira Kaya, René Werkmeister, Reinhard Told, Stefan Palkovits, Gabriele Fuchsjäger-Mayrl, Gerhard Garhöfer and Leopold Schmetterer

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A28

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Herb-drug interactions: the influence of essential oil of caraway (Carum carviL.) on the pharmacokinetics of paracetamol

Authors: Isidora Samojlik, Kornelia Ðaković-Švajcer, Biljana Božin and Momir Mikov

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A27

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Improving the low solubility of resveratrol

Authors: Milica T Atanacković, Ljiljana C Gojković-Bukarica and Jelena M Cvejić

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A25

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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The atypical cannabinoid O-1602 shows antitumorigenic effects in colon cancer cells and reduces tumor growth in a colitis-associated colon cancer model

Authors: Julia Kargl, Johannes Haybäck, Angela A Stančić, Gunther Marsche, Ákos Heinemann and Rudolf Schicho

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A23

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Bioactivation of nitroglycerin is determined by the subcellular localization of aldehyde dehydrogenase-2

Authors: Regina Neubauer, Corina Madreiter, Matteo Beretta, Gerald Wölkart, Kurt Schmidt, Astrid Schrammel and Bernd Mayer

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A21

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Characteristics of low affinity high capacity histamine uptake into neonatal rat astrocytes

Authors: Mojca Kržan, Maša Novak, Sergej Pirkmajer and Katja Perdan-Pirkmajer

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A19

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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A PET microdosing study with the P-glycoprotein inhibitor tariquidar

Authors: Martin Bauer, Markus Zeitlinger, Cécile Philippe, Johann Stanek, Wolfgang Wadsak, Markus Mitterhauser, Georgios Karanikas, Markus Müller and Oliver Langer

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A17

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Uremia alters HDL composition and cholesterol efflux capacity

Authors: Michael Holzer, Ruth Birner-Grünberger, Tatjana Stojaković, Dalia El-Gamal, Veronika Binder, Christian Wadsack, Ákos Heinemann and Gunther Marsche

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A15

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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The role of CB₂receptor ligands in human eosinophil function

Authors: Robert Frei, Eva Sturm and Ákos Heinemann

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A13

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Influence of different Hypericum perforatumL. preparations on pharmacokinetic and pharmacodynamic properties of pentobarbital, diazepam and paracetamol

Authors: Aleksandar Rašković, Nebojša Stilinović and Momir Mikov

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A11

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Protective effect of silymarin on doxorubicin-induced cardiotoxicity in rats

Authors: Nebojša Stilinović, Aleksandar Rašković, Momir Mikov, Saša Vukmirović and Boris Milijašević

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A9

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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The bile acid membrane receptor TGR5: a novel pharmacological target in metabolic syndrome

Authors: Vanesa Stepanov, Karmen Stankov and Momir Mikov

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A7

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Remarkably lower consumption of antidepressants in Serbia in comparison with Finland

Authors: Maja Stojančević, Milica Paut Kusturica, Bojan Stanimirov, Nebojša Pavlović, Zdenko Tomić, Ana Sabo and Momir Mikov

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A5

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Differences in the use of medicines for peptic ulcer and gastro-esophageal reflux disease between Serbia, Croatia and Sweden

Authors: Bojan Stanimirov, Karmen Stankov, Nebojša Pavlović, Milica Paut Kusturica, Maja Stojančević, Ana Sabo and Momir Mikov

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A4

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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Methadone-drugs interactions: possible causes of methadone-related deaths

Authors: Vesna Mijatović, Isidora Samojlik, Stojan Petković and Nikša Ajduković

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A2

Content type: Meeting abstract Published on: 17 September 2012

This article is part of a Supplement: Volume 13 Supplement 1
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